Publications

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Geographics and bacterial networks shape the global urban sewage resistome

Published in In review, 2025

Study of sewage resistomes to identify regional differences

Recommended citation: Martiny, H.-M., Munk, P., Fuschi, A., Becsei, A., Pyrounakis, N., Brinch, C., Global Sewage Consortium, Larsson, D G J., Koopmans, M., Remondini, D., Csabai, I., Aarestrup, F. M. (2025). Geographics and bacterial networks shape the global urban sewage resistome. In review.
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Utilizing co-abundances of antimicrobial resistance genes to identify potential co-selection in the resistome

Published in Microbiology Spectrum, 2024

This preprint details how pairwise correlation of antimicrobial resistance abundances highlights potential co-selection occuring in different environments at a global scale.

Recommended citation: Martiny, H. M., Munk, P., Brinch, C., Aarestrup, F. M., Calle, M. L., & Petersen, T. N. (2024). Utilizing co-abundances of antimicrobial resistance genes to identify potential co-selection in the resistome. Microbiology Spectrum, 12(7), e04108-23.
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ARGprofiler—a pipeline for large-scale analysis of antimicrobial resistance genes and their flanking regions in metagenomic datasets

Published in Bioinformatics, 2024

Our workflow ARGprofiler is designed to handle large quantities of metagenomic datasets to profile antimicrobial resistance genes and their flanking regions

Recommended citation: Martiny, H. M., Pyrounakis, N., Petersen, T. N., Lukjančenko, O., Aarestrup, F. M., Clausen, P. T., & Munk, P. (2024). ARGprofiler—a pipeline for large-scale analysis of antimicrobial resistance genes and their flanking regions in metagenomic datasets. Bioinformatics, 40(3), btae086.
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A curated data resource of 214K metagenomes for characterization of the global antimicrobial resistome

Published in PLOS BIOLOGY, 2022

This paper details the large collection of 214K metagenomes that we curated to analyze the distribution of antimicrobial resistance genes at a global scale.

Recommended citation: Martiny, H. M., Munk, P., Brinch, C., Aarestrup, F. M., & Petersen, T. N. (2022). A curated data resource of 214K metagenomes for characterization of the global antimicrobial resistome. PLoS biology, 20(9), e3001792.
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Global distribution of mcr gene variants in 214K metagenomic samples

Published in mSystems, 2022

This paper analyzes the abundance levels of nine mcr gene variants in metagenomic samples from different locations, years and sampling hosts sources within 214K metagenomes.

Recommended citation: Martiny, H. M., Munk, P., Brinch, C., Szarvas, J., Aarestrup, F. M., & Petersen, T. N. (2022). Global Distribution of mcr Gene Variants in 214K Metagenomic Samples. Msystems, e00105-22.
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NetSolP: predicting protein solubility in E. coli using language models

Published in Bioinformatics, 2022

This study aims to predict solubility and usability of proteins by applying deep learning protein language models.

Recommended citation: Vineet Thumuluri, Hannah-Marie Martiny, Jose J Almagro Armenteros, Jesper Salomon, Henrik Nielsen, Alexander Rosenberg Johansen, NetSolP: predicting protein solubility in Escherichia coli using language models, Bioinformatics, Volume 38, Issue 4, 15 February 2022, Pages 941–946, https://doi.org/10.1093/bioinformatics/btab801
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Deep protein representations enable recombinant protein expression prediction

Published in Computational Biology and Chemistry, 2021

Protein representations improve the success of predicting whether a protein can be recombinantly expressed in Bacillus subtilis.

Recommended citation: Martiny, H. M., Armenteros, J. J. A., Johansen, A. R., Salomon, J., & Nielsen, H. (2021). Deep protein representations enable recombinant protein expression prediction. Computational Biology and Chemistry
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